complement activation pathway中文什么意思

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An array of regulatory proteins have been found , which inhibit the formation of central enzymes involved in early stages of the complement activation pathway . these include membrane cofactor protein ( mcp cd46 ) , decay - accelerating factor protein ( daf cd5 5 ) , complement receptor 1 ( cr1 , cd35 ) , as well as cd59 , which inhibits formation of the membrane attack complex during later stages . these regulatory factors are widely expressed and abundant on many cells , and in fluids of reproductive system
目前發(fā)現(xiàn)，機(jī)體多種細(xì)胞以及生殖系統(tǒng)的體液中表達(dá)和分泌豐富的補(bǔ)體調(diào)控蛋白，包括作用于補(bǔ)體活化早期階段的cd55 、 cd46 、 cd35和作用于補(bǔ)體活化終末階段的cd59 ，它們分別通過抑制補(bǔ)體活化過程中關(guān)鍵的c3 、 c5轉(zhuǎn)化酶和抑制形成膜攻擊單位，抵抗補(bǔ)體對自身組織細(xì)胞的攻擊。

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